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• 產(chǎn)品描述： Faropenem sodium是具有口服活性的β-內(nèi)酰胺抗生素，用于研究治療肺結(jié)核和社區(qū)獲得性肺炎的試驗(yàn)中。

• 靶點(diǎn)： Antibacterial;Antibiotic

• 細(xì)胞實(shí)驗(yàn)： Cell lines: RAW macrophages Concentrations: 7, 28, or 56 μg/ml Incubation Time: -- Method: RAW macrophages were grown in Dulbecco modified Eagle medium containing l-glutamine and sodium pyruvate (PAA Laboratories) supplemented with 10% fetal bovine serum. About 2.5 × 104 cells were seeded into each well of a 48-well plate and were infected with green fluorescent protein (GFP)-expressing M. tuberculosis (MTB_NDT1) at a multiplicity of infection (MOI) of 10:1 for 4 h. After infection, the monolayers were washed three times with fresh medium to remove nonadherent bacteria and then exposed to fresh medium with or without isoniazid (0.75 μg/ml), faropenem (7, 28, or 56 μg/ml), or meropenem (5, 25, or 50 μg/ml) plus clavulanate (2.5 μg/ml). Medium (containing antibiotics) was changed every 24 h. At various time points, macrophages were washed once with 1× PBS and then lysed using 0.5% Triton X-100. The macrophage lysates were diluted in PBS containing 0.05% Tween 80, serial dilutions were plated on 7H10 agar, a

• 動(dòng)物實(shí)驗(yàn)： Animal Models: Adult female C57BL/6J mice Dosages: 500 mg/kg Administration: oral

• 參考文獻(xiàn)：
  1. Dhar N, et al. Antimicrob Agents Chemother. 2015, 59(2):1308-19.

• 溶解性： Soluble  in  DMSO、H2O

• 保存條件： -20℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	3.254 ml	16.271 ml	32.542 ml
  5 mM	0.651 ml	3.254 ml	6.508 ml
  10 mM	0.325 ml	1.627 ml	3.254 ml
  50 mM	0.065 ml	0.325 ml	0.651 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *