S80158 |
IPI-145 (INK1197) |
源葉(MedMol) | 99% |
- 提示:詳情請(qǐng)下載說(shuō)明書。
- 產(chǎn)品描述: Duvelisib (IPI-145) is a selectivite p100δ inhibitor with IC50 of 2.5 nM, 27.4 nM, 85 nM and 1602 nM for p110δ, P110γ, p110β and p110α, respectively
- 靶點(diǎn): p110δ:2.5 nM (IC50);p110γ:27.4 nM (IC50);p110β:85 nM (IC50);p110α:1602 nM (IC50);PI3K
- 參考文獻(xiàn):
1. Pillinger G, et al. Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection. Oncotarget. 2016 Jun 28;7(26):39784-39795. 2. G?ckeritz E, et al. Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells. Int J Cancer. 2015 Nov 1;137(9):2234-42.
- 溶解性: DMSO : ≥ 41 mg/mL (98.35 mM)
- 保存條件: -20℃
- 配置溶液濃度參考:
1mg 5mg 10mg 1 mM 2.399 ml 11.994 ml 23.989 ml 5 mM 0.48 ml 2.399 ml 4.798 ml 10 mM 0.24 ml 1.199 ml 2.399 ml 50 mM 0.048 ml 0.24 ml 0.48 ml
- 注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。
輸入產(chǎn)品批號(hào):
本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系,公式為:
質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)