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S80107

HYDROXY ITRACONAZOLE

源葉(MedMol) 98%
  • 英文名:
  • HYDROXY ITRACONAZOLE
  • 別名:
  • 羥基伊曲康唑(伊曲康唑代謝物);羥基伊曲康唑;伊曲康唑2-羥基代謝物;HYDROXY ITRACONAZOLE;3H-1,2,4-Triazol-3-one, 4-4-4-4-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxyphenyl-1-piperazinylphenyl-2,4-di
  • CAS號(hào):
  • 112559-91-8
  • 分子式:
  • C35H40Cl2N8O4
  • 分子量:
  • 707.649
品牌貨號(hào)產(chǎn)品規(guī)格價(jià)格(RMB) 庫(kù)存(上海) 北京 武漢 南京 數(shù)量計(jì)量單位 加入購(gòu)物車(chē)...
源葉(MedMol) S80107-1mg 98% ¥2000.00元 2 - - - EA 加入購(gòu)物車(chē)
源葉(MedMol) S80107-5mg 98% ¥6000.00元 2 - - - EA 加入購(gòu)物車(chē)
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產(chǎn)品介紹

參考文獻(xiàn)

質(zhì)檢證書(shū)(COA)

摩爾濃度計(jì)算器

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  • 提示:詳情請(qǐng)下載說(shuō)明書(shū)。
  • 產(chǎn)品描述: Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
  • 靶點(diǎn): Antifungal
  • 體內(nèi)研究:
    The plasma concentration of Hydroxy Itraconazole is weakly dependent on the dose of ITZ, most likely because the process that forms Hydroxy Itraconazole is saturated. Serum albumin and GFR may alter the pharmacokinetics of ITZ and Hydroxy Itraconazole. Antifungal activity should be discussed while taking into account not only the plasma concentration of ITZ but also that of Hydroxy Itraconazole. However, the pharmacokinetics of Hydroxy Itraconazole is similar to that of ITZ in immunocompromised patients taking an oral solution of ITZ. Since the plasma concentrations of ITZ and Hydroxy Itraconazole are closely correlated, determining the plasma concentration of either should be sufficient from a clinical point of view
  • 參考文獻(xiàn):
    1. Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32.
  • 溶解性: DMSO  :  100  mg/mL  (138.58  mM;  Need  ultrasonic)    H2O  :  1  mg/mL  (1.39  mM;  ultrasonic  and  warming  and  heat  to  80°C)
  • 保存條件: 2-8℃
  • 配置溶液濃度參考:
    1mg 5mg 10mg
    1 mM 1.413 ml 7.066 ml 14.131 ml
    5 mM 0.283 ml 1.413 ml 2.826 ml
    10 mM 0.141 ml 0.707 ml 1.413 ml
    50 mM 0.028 ml 0.141 ml 0.283 ml
  • 注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶(hù)參考交流研究之用。
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本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系,公式為:


質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)


  • =
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