S80027 |
SGX-523 |
源葉(MedMol) | 99% |
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- 產(chǎn)品描述: SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity
- 靶點(diǎn): c-Met/HGFR;Raf;p38MAPK;c-Met/HGFR;Bcr-Abl
- 體內(nèi)研究:
SGX523 exhibits antitumor activity in vivo. SGX523 inhibits MET-dependent tumor growth
- 參考文獻(xiàn):
1. Buchanan SG, et al. SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol Cancer Ther, 2009, 8(12), 3181-3190.
- 溶解性: DMSO : 30 mg/mL (83.47 mM; Need ultrasonic)
- 保存條件: -20℃
- 配置溶液濃度參考:
1mg 5mg 10mg 1 mM 2.782 ml 13.911 ml 27.823 ml 5 mM 0.556 ml 2.782 ml 5.565 ml 10 mM 0.278 ml 1.391 ml 2.782 ml 50 mM 0.056 ml 0.278 ml 0.556 ml
- 注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。
輸入產(chǎn)品批號(hào):
本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系,公式為:
質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)